NPH insulin

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Description

NPH insulin for sale 

     Neutral Protamine Hagedorn insulin, also known as isophane insulin, is an intermediate-acting insulin given to help control blood sugar levels in people with diabetes. NPH insulin for sale
It is used by injection under the skin once to twice a day  and also onset of effects is typically in 90 minutes and they last for 24 hours.
Trade name: Novolin N, Humulin N, Insulatard, others. NPH insulin for sale
Duration of action: 24 hours
Onset of action: 90 minutes

Dosage Forms & Strengths

injectable suspension

  • 100units/mL (3mL)
  • 100units/mL (10mL)
Type 1 Diabetes Mellitus
Suggested guidelines for beginning dose
  • Usual daily maintenance range is 0.5-1 unit/kg/day SC in divided doses; nonobese may require 0.4-0.6 unit/kg/day; obese may require 0.8-1.2 units/kg/day. NPH insulin for sale
Type 2 Diabetes Mellitus

Suggested guidelines for beginning dose: 0.2 unit/kg/day

Morning
  • Give two thirds of daily insulin SC
  • Ratio of regular insulin to NPH insulin 1:2
Evening
  • Give one third of daily insulin SC
  • Ratio of regular insulin to NPH insulin 1:1
Dosing Considerations

Dosage of human insulin, which is always expressed in USP units, must be based on the results of blood and also urine glucose tests and must be carefully individualized to optimal effect

So, Dose adjustments should be based on regular blood glucose testing

Adjust to achieve appropriate glucose control

Blood sugar patterns (>3 days)
  • Look for consistent pattern in blood sugars for >3 days
  • For the same time each day: Compare blood glucose level
  • For each time of day: Calculate blood glucose range
  • Calculate median blood glucose
  • Consider eating and also activity patterns during day
Blood glucose adjustments
  • similarly adjust only 1 insulin dose at a time
  • Correct hypoglycemia first
  • Correct highest blood sugars next
  • If all blood sugars are high (within 2.75 mmol/L [50 mg/dL]): Correct morning fasting blood glucose first
  • However change insulin doses in small increments: Type 1 diabetes (1-2 unit change); type 2 diabetes (2-3 unit change)
Sliding scales
  • Therefore many sliding scales exist to determine exact insulin dose based on frequent blood above all glucose monitoring
  • Commonly written for q4hr blood glucose test
  • Sliding scale coverage usually begins after blood glucose >11 mmol/L (200 mg/dL)
  • So, if coverage is need q4hr x 24 hr, and so then base insulin dose is adjusted first; sliding scale doses may be adjust upwards as well

Additional information

NPH insulin

Novolin N FlexPen (3 mL carton; 100 iU/mL) $250 per carton of 5 pens, Novolin N vial (10 mL; 100 iU/mL) $120 per vial, Humulin N (10 mL vial; 100 iU/mL) $160 per vial, Humulin N KwikPen (3 mL; 100 iU/mL) $120 per pen

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