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Clonitrazolam consists of a benzene ring bonded to a diazepine ring. Similarly Diazepine rings are seven-member with two nitrogen constituents located at R1 and R4.
However A nitrogen group, NO2, replaces clonazolam’s benzyl ring at R8. Above all The diazepine ring bonds at R6 to a 2-chlorinated phenyl ring. Clonazolam also contains a 1-methylated triazole ring fused to and incorporating R1 and R2 of its diazepine ring. All triazolobenzodiazepine drugs with the “-zolam” suffix have the triazole ring.
Nevertheless Being a subclass of benzodiazepines containing a nitrogen (NO2-) group, other nitrobenzodiazepines include clonazepam and flunitrazepam.
Product Name: Clonitrazolam
Other Name(s): Clonazolam
IUPAC Name: 6-(2-chlorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Active Ingredient(s): Clonazolam
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Clonitrazolam has varying legal statuses around the world. In Sweden, it has been propose to be made a hazardous substance. In the United Kingdom.
Similarly it has sufficient cross-reactivity to trigger a positive result on urine screening
using common commercial benzodiazepine immunoassays. However, these immunoassays
cannot distinguish between prescribed benzodiazepines and clonazolam
Above the elimination half-life of Clonitrazolam is estimated to be 3.6 hours and is extensively metabolized and is mainly excreted as its amino and acetamino metabolites . It has a medium-length onset of action (20–60 minutes)
.In other words the main metabolites are 7-aminoclonazolam, hydroxyclonazolam, and 7-acetamidoclonazolam .
However both metabolites and also parent compound are eliminate in the urine. No information is available on volume of distribution.